ISSN: 1859 - 2872
The effectiveness of the managing cardiovascular drug - disease interactions in outpatient at Ha Dong General Hospital
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Abstract
Objective: To analyze the effectiveness of managing cardiovascular drug-disease interactions in outpatients through clinical pharmacy activity at Ha Dong General Hospital. Subject and method: Intervention study, comparing the pre-intervention and post-intervention periods through warnings of cardiovascular drug-disease interaction pairs on the software when doctors prescribe. During the pre-intervention phase, the research team reviewed cardiovascular drug-disease interactions from September 2022 to October 2022. The post-intervention phase, on the other hand, evaluated the effectiveness of drug-disease interaction management from January 2023 to February 2023. Result: The results showed that the patients in this study were elderly (mean age: 67.4 ± 11.5 in the pre-intervention period and 68.8 ± 10.2 in the intervention period), using many drugs in both stages, respectively: 4.6 ± 2.0 and 3.2 ± 13. After the pharmacist intervened, the number of cardiovascular drug-disease interactions reduced from 49 (0.213%) to 7 (0.029%). Interaction pairs that still occurred after interfering were thiazide - Severe renal failure, bisoprolol - Severe asthma, aspirin - Peptic ulcer. Conclusion: The warning system for cardiovascular drug-disease interactions in the software, triggered when doctors prescribe medications, has been effective. The rate of these interactions in the post-intervention period significantly decreased compared to the pre-intervention period (p<0.05)
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References
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