ISSN: 1859 - 2872
Initial result of radio frequency ablation for treatment of benign thyroid nodules in 108 Military Central Hospital
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Abstract
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Objective: To evaluate prospectively the safety and efficacy of this method in a large patient cohort following it’s introduction in 108 Military Central Hospital. Subject and method: Peri and post - interventional complications were analyzed for 937 patients with 1175 benign thyroid nodules. Efficacy and clinical examination determined at 3, 6, 12 - month post treatment, respectively. All treatments were perfomed with monopolar internally cooled 18G radiofrequency electrode using a free-hand, moving shot technique following subcutaneous and local perithyroidal anesthesia. Result: 93.4% patients were female with 55% at 40 - 60 years old. MVRR (Mean volume reduction rate) at 3, 6, 12 months were 66.2 ± 21.3%; 71.7 ± 21.1% and 72.7 ± 21.0% respectively. 80.9% nodules had volume reduction over 50% after 12 months. MCS (Mean cosmetic score) changes from 1.2 ± 1.7 to 0.4 ± 0.7 and MV (Mean volume) reduces from 6.1± 12.0mL to 1.8 ± 4.3mL (p<0.05) after 12 months (p<0.05). 91% patients had VAS score under 4. Overal complication rate was 4% include local skin burn (0.3%), Horner syndrome (0.1%), hematoma (0.2%), hemorrhage (0.2%) and hoarseness (3.2%). Almost complications had recoverd after 3 - 6 months. Conclusion: RFA is safe and effective in treating benign thyroid nodules: Reduce 72.7% nodule volume after 12 months. Complications rate is 4%, almost complication had recoverd after 3 - 6 months.
Keywords: Thyroid nodules, benign, RFA, radiofrequency, efficacy, treatment, complication.
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References
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