Điều trị ung thư tuyến giáp thể nhú sau phẫu thuật, di căn phổi bằng I-131 ở người trưởng thành dưới 45 tuổi: Báo cáo 20 trường hợp lâm sàng

Abstract

Objective: To investigate clinical characteristics, results of treatment of 20 patients under 45 years old post-surgical 131-I treatment of pulmonary metastases from papillary thyroid carcinoma. Subject and method: Retrospective study 20 cases (from 18-45 years old) papillary thyroid carcinoma with discovering lung metastasis after total thyroidectomy or subtotal thyroidectomy were treated by I-131 after surgery in HCM Cancer Hospital from 2013 to 2022. Result: 90% of cases had metastatic lymph nodes. Rate of ipsilateral, bilateral lymph nodes metastases were 50% and 40% respectively. 20% of total patients need to surgical lymph nodes dissection second time. Tumors with size under 4cm takes 60% and 85% of tumor had extracapsule and infiltrate extra gland. 75% patients had been treated over total dosage of 1000mCi I-131. Conclusion: 70% of patients structure incomplete response and 5% response biochemistry imcompletely. There are not suppresion of the bone marrow.