Khảo sát vai trò của 18FDG PET/CT trong chẩn đoán giai đoạn ung thư thực quản trước điều trị tại Bệnh viện Đà Nẵng

Abstract

Esophageal cancer is one of the most mortal malignancies worldwide. Therefore, accurate pre-treatment staging of esophageal carcinoma, which subsequently guides the stage-adapted treatment approach, is critical in optimizing the survival outcomes. Research objectives: 1. Describe the characteristics of  PET/CT images of pre-treatment staging of esophageal carcinoma at Da Nang hospital. 2. Evaluate the role of PET/CT in staging of esophageal cancer before treatment at Da Nang Hospital. Subject and method: Esophageal cancer patients who were confirmed by pathology and underwent PET/CT pre-treatment at the Nuclear Medicine Department of Da Nang Hospital from 01/2020-12/2021; Method: A cross-sectional descriptive study. Result: The primary tumor strongly uptake FDG in all 3 esophageal segments: upper third, middle and lower third with SUVmax values of 16.89 ± 5.33, 13.81 ± 4.11, 14.56 ± 4.81, respectively. The mean SUVmax value was proportional to the tumor length (r = 0.3). The number of metastatic nodes was positively correlated with tumor length (r = 0.6). After PET/CT scan, the number of patients in stages I, II, III all was decreased, the number of patients in stage IV was increased. 23/45 patients (accounting for 51.1%) had the stage of the disease changed. Conclusion: PET/CT significantly improves the accuracy of pre-treatment staging of esophageal carcinoma, contributing to improving the efficiency of diagnosis and treatment for patients.