Theranostic trong y học hạt nhân: Hiện tại và triển vọng

Abstract

The theranostic approach couples diagnostic imaging and therapy using the same molecular or at least very similar molecules. The imaging for detection of potential targets enable to not only diagnosis but predict if a patient will benefit from particular treatment. Theranostics in nuclear medicine refers to the use of radioactive compounds to image biologic phenomena radioactive compounds to image biologic phenomena by means of expression of specific disease targets and then to use specifically designed agents to deliver ionizing radiation to the tissues that express these targets. The nuclear theranostic approach has been increasing interest and gained importance in parallel to the growth in molecular imaging and personalized medicine, improving patient treatment selection, prediction of response and toxicity… in various malignant diseases. The paper provide an overview of theranostic approaches in nuclear medicine, starting with a review of the main concepts and the progress of theranostic agents since early applications and disscus the developments and future directions of theranostic.