ISSN: 1859 - 2872
Lymph node metastasis status in the middle-lower third esophageal cancer patient received preoperative neo-adjuvant chemoradiation therapy combined transthoracic video-assisted esophagectomy
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Abstract
Objective: To evaluate the distribution of metastatic lymph nodes in the middle- and lower third esophageal cancer patient who received preoperative neoadjuvant chemoradiation combined transthoracic video-assisted esophagectomy. Subject and method: A retrospective, randomized, interventional study. From March 2019 to September 2022, 76 patients with middle-lower third esophageal cancer received neo-adjuvant chemoradiation therapy, followed by transthoracic video-assisted esophagectomy at the Digestive Surgery Department, 108 Military Central Hospital was included in the study. The data on patient characteristics, pathology results were recorded and analyzed using SPSS 16.0 software. Result: All patients were male. 7.9% of patients did not complete 5 chemotherapy courses. 100% were irradiated with a total dose of 41.4Gy. The average number of lymph nodes removed was 21.08 ± 10.83. The total number of removed lymph nodes was 1602 nodes, the number of metastatic nodes was 72 nodes. The average number of metastatic chest lymph nodes, the average rate of metastatic chest lymph nodes was lower than the average number of metastatic abdominal lymph nodes, the average rate of metastatic abdominal lymph nodes. There was no difference in the rate of lymph node metastasis at tumor invasion (T). The rate of lymph node metastasis, the rate of abdominal lymph node metastasis, the rate of metastatic chest lymph node in the lower third was higher than that in the middle third, but no statistical significance. In the abdomen, the number of metastatic abdominal lymph nodes outside the irradiation field was higher than the number of metastatic nodes in the irradiated area. Conclusion: After neoadjuvant chemotherapy and radiotherapy, the rate of lymph node metastasis was 4.49%. There was no difference in the rate of lymph node metastasis at tumor invasion levels from T0-T4. Systemic lymph node dissection is necessary.
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References
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