ISSN: 1859 - 2872
Initial results of microbiological characteristics isolated from bile by ERCP in acute cholangitis due to common bile duct stones patients
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Abstract
Objective: To identify microbiological characteristics isolated from bile by ERCP in acute cholangitis due to common bile duct stones patients and the characteristics of multi-drugs-resistant bacteria. Subject and method: From Jan 2022 to March 2023, ninety-three patients with acute cholangitis caused by common bile duct stones who underwent ERCP and collect bile fluid to culture of aerobic bacteria. Bacteria species and antibiotic susceptibility are identified by using the VITEK 2 compact test. Result: Mean age: 67.43 ± 1.49. Positive bile culture was 87.1%. Mostly monomicrobial and 86.4% was Gram negative strains. Escherichia coli (E. coli) was the most common species isolated in both bile fluid and blood. E. coli had highly sensitive to amikacin, carbapenems, pipercillin - tazobactam; considerable resistance to the 3rd and 4th cephalosporin, quinolon. Among patients with positive bile and blood culture, the rate of matching for at least 1 species reached to 88.9%. Conclusion: E. coli which is the most frequent bacteria in acute cholangitis due to common bile duct stones, still high sensitive to amikacin, carbapenems. Microbial isolated from bile fluid can be considered for using proper antibiotics.
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References
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