ISSN: 1859 - 2872
Efficacy of narrow-band ultraviolet B in treatment of patients with vitiligo at Can Tho Hospital
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Abstract
Objective: To evaluate the therapeutic efficacy of narrow-band ultraviolet B (NB-UVB) in vitiligo. Subject and method: Intervention cohort study on 58 patients with vitiligo diagnosed by clinical findings at Can Tho Hospital of Dermato - Venereology from 05/2020 to 11/2020. The patients were treated with UVB 308nm once a week with initial dose according to recommendation of manufacturer (VTRAC, Photomedex, USA), then adjusted the dose at which obtaining a minimum erythema dose (MED). The therapeutic efficacy was evaluated after 1 month, 2 months and 3 months by using VASI. Result: 67.2% patients with duration of vitiligo 6 months to 2 years. 20.7% patients with VIDA +1 and +2. After 1 month, the rate of good response was 8.7% and increased to 72.5% after 3 months (p<0.05). Lesions on face and neck were better responsed than those on other positions. The focal vitiligo was better responsed to the treatment than the generalized type. Side effect was not frequent. The ratios of patients with perilesional hyperpigmentation, persistent erythema and blister were 8.6%, 6.8% and 3.4%, respectively. Conclusion: Narrow-band UVB 308nm therapy is effective and safe in the treatment of vitiligo.
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References
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