Study on the alterations of left atrial volume and strain by echocardiography in patients with chronic kidney disease
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Abstract
Objective: To understand the alteration of left atrial volume and strain across different stages of renal failure. Subject and method: The study was conducted on 150 subjects with chronic kidney failure who were treated at Bach Mai Hospital and 30 healthy subjects from April to October 2022. All patients were clinically examined. Transthoracic echocardiography was performed to assess left atrial volume and strain. Result: The mean age of patients with chronic kidney disease was 48.4 ± 18.7 years old. The mean glomerular filtration rate was (44.48 ± 40.6) ml/min/1.73m2. Left atrial diameter (LAD), volume index in 4-chamber view (LAVimax 4B), in 2-chamber view (LAVimax 2B) and biplane (LAVimax biplane) increased gradually with the progressive stages of chronic kidney disease (p<0.05). Atrial strain for reservoir and conduit functions decreased with the decline of renal function (p<0.05) but the LA contractility was insignificantly. Conclusion: The left atrial volume tends to increase and its function (reservoir, conduit) tends to decrease across stages of renal failure.
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References
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