Biliary complications after a right lobe in living donor liver transplantation

  • Lê Văn Thành Bệnh viện Trung ương Quân đội 108
  • Vũ Văn Quang Bệnh viện Trung ương Quân đội 108

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Keywords

Donor right hepatectomy, living donor liver transplantation, biliary complications

Abstract

Objective: To evaluate biliary complications post-operative right hepatectomy in living donor liver transplantation. Subject and method: A retrospective study of 148 cases of donors who underwent right hepatectomy from October 2017 to October 2022 at 108 Military Central Hospital. Result: Biliary anatomical variation: Type I was the most common type with 126 (85.14%) cases; type II: 8 (5.41%) cases; type III: 11 (7.44%) cases; type IV 3 (2.03%) cases. All the 7 cases having biliary complications were in type 1 group: 5 (3.38%) cases of bilary leakage treated with drainage, 4 of which was successful and 1 was unsuccessful and needed reoperation; 02 (1.35%) cases had biliary stenosis treated with stent placement via endoscopic retrograde cholangiopancreatography (ERCP). Based on Clavien-Dindo classification for complications, level IIIa was witnessed in 6 (4.05%) cases, IIIb in 1 (0.68%) case. No cases of mortality in the donors of our study. Conclusion: Biliary complications is the most common challenge post-operative right hepatectomy in ling donor liver transplantation and can be succesfully treated with drainage or ERCP.

Article Details

References

1. Yamaoka Y, Washida M, Honda K et al (1994) Liver transplantation using a right lobe graft from a living related donor. Transplantation 57: 1127-1130.
2. Shiffman ML, Brown RS, Olthoff KM et al (2002). Living donor liver transplantation: Summary of a conference at The National Institutes of Health. Liver Transpl 8: 174-188.
3. Lee JG, Lee KW et al (2017) Korean organ transplantation registry study. Liver Transpl 23(08): 999-1006.
4. Beavers KL, Sandler RS, Shrestha R (2002) Donor morbidity associated with right lobectomy for living donor liver transplantation to adult recipients: A systematic review. Liver Transpl 8(2): 110-117.
5. Giovanni Varotti G, Gondolesi GE, Goldman J, Wayne M et al (2004) Anatomic variations in liver living donors. J Am Coll Surg 198 (4): 577-582.
6. Woo HY, Lee IS, Chang JH, Youn SB, Bae SH, Choi JH et al (2018) Outcome of donor biliary complications following living donor liver transplantation. Korean J Intern Med 33: 705-715.
7. Mathew JS, Manikandan K et al (2017) Biliary complications among live donors following live donor liver transplantation. The Surgeon, https://doi.org/10.1016/j.surge.2017.08.005.
8. Yazumi S, Chiba T (2005) Biliary complications after a right lobe living donor liver transplantation. J Gastroenterol 40: 861-865.
9. Özbilgin M, Ünek T, T. Egeli T, Ag!alar C, Ag!alar, Ozkardesler S, Karadeniz E, Ellidokuz H, Obuz F, and Astarcıog!lu I (2017) Complications in donors using right liver graft: Analysis of 280 consecutive cases. Transplantation Proceedings 49: 580-586.
10. Agarwal N, Sharma BC, Garg S, Kumar R, Sarin SK (2006) Endoscopic management of postoperative bile leaks. Hepatobiliary Pancreat Dis Int 5: 273-277.