ISSN: 1859 - 2872
Correlation between the ratio of blood cells and glomerular filtration rate in multiple myeloma patients with renal failure treated at Bach Mai Hospital
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Abstract
Objective: Analysis of the correlation between the ratio of blood cells and glomerular filtration rate in multiple myeloma patients with renal failure. Subject and method: Retrospective cohort sudy. 51 patients with multiple myeloma with renal failure at the Hematology and Blood Transfusion Center of Bach Mai Hospital from 2019 to 2022 were analyzed for pre-treatment indicators including: NLR (neutrophil/leukocyte ratio) lymphocytes), LMR (lymphocyte/monocyte ratio), NMLR (neutrophil + monocyte/lymphocyte ratio), HGB (hemoglobin concentration), PLR (platelet/white blood cell ratio), glomerular filtration rate (GFR) before and after treatment. Result: The median age of the patients was 58.5 years old. The males of patient group were 64.7%, the most common type disease was light chain multiple myeloma (49.1%), patients with NLR ≥ 2, LMR < 3.6, HGB < 100 had lower GFR (before and after treatment) than those with NLR < 2, LMR ≥ 3.6, HGB ≥ 100. NMLR was higher in patients with GFR < 15 (ml/ph/1,73m2). We had not found the difference in GFR by PLR. Conclusion: High NLR, NMLR, low LMR, HGB are poor prognostic factors for glomerular filtration rate and the recovery of GFR after treatment, in multiple myeloma patients with renal failure.
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