ISSN: 1859 - 2872
The difference between charateristic of septic patients caused by Escherichia coli and Klebsiella pneumoniae
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Abstract
Objective: To evaluate the difference between clinical, subclinical manifestation of septic patients caused by E. coli and K. pneumoniae. Subject and method: In total, 165 septic patients caused by E. coli (115 patients) and K. pneumoniae (50 patients) at 108 Military Central Hospital from October 2014 to May 2016 were enrolled in this study. Blood culture were performed at the Microbiology Department of 108 Military Central Hospital with routinely protocol. Result: Sepsis was frequent appeared in patients with pre-condition (88.9%). E. coli sepsis was common associated with cancer (30.4%), hypertension (28.7%) and diabetes (17.4%), while K. pneumoniae sepsis was 16.0%, 22.0% and 20.0%, respectively. The most of sepsic patients presented primary source infections (85.3%). The most of primary source of sepsis caused by E. coli were urinary tract infection (34.8%), biliary tract infection (31.3%); while related intervention (26.0%), respiratory infection (24.0%) and biliary tract infection (18.0%) were the most common primary source of sepsis caused by K. pneumoniae. Length of stay in hospital of K. pneumoniae sepsis was significant longer than E. coli sepsis (27.7 ± 27.6 vs 19.9 ± 14.7 days, p=0.02). Ratio of shock, mortality, inflammatory markers and SOFA scores were not significant difference between septic patients caused by E. coli and K. pneumoniae. Conclusion: The primary source of infections was difference between sepsis caused by E. coli and K. pneumoniae; septic patients caused by K. pneumoniae seems to be more severe compared to septic patients caused by E. coli.
Keywords: Sepsis, Escherichia coli, Klebsiella pneumoniae.
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References
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