Comparison between dose distribution on treatment volume and organs at risk in the planning for left - sided breast cancer radiotherapy using free breathing and deep inspiration breath hold techniques at 108 Military Central Hospital
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Abstract
Objectieve: To compare dose distribution on treatment volume and organs at risk in the planning with left - sided breast cancer radiotherapy using Free breath (FB) and Deep inspiration breath hold (DIBH) techniques in order to to evaluate the diametric benefit of DIBH technique for reservation of organs at risk (OAR). In addition, to find out pre-treatment factor affecting the treatment outcome to recommend for the selection of patient using DIBH. Subject and method: 25 left - sided breast cancer patients who previously underwent with DIBH on Truebeam Stx linac are selected. Simulated CT data in two phases of free breathing (FB) and DIBH were used to replan on Eclipse v13.6 by Field in field technique. The dose prescription were 42Gy in 15 fraction for planning target volume (PTV). The main objectives were 100% mean dose to the PTV and maximum dose £ 107%. The dose distribution of OARs on Dose Volume Histogram (DVH) and target Homogenety Index (HI) were compared between FB and DIBH plans. Result: Both FB and DIBH plans had similar of HI. Using DIBH, the mean dose and V25 of heart were better than FB plans (p<0.05). There were no significant differences in OARs such as the contralateral lung, contralateral breast, and spinal cord. The distance between the FB and DIBH phase is 1.6cm. Conclusion: The DIBH is an effective technique in the reduction of the heart dose and ipsilateral lung for tangentially treated left – sided breast cancer patients.
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References
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