ISSN: 1859 - 2872
Association between plasma magnesium levels and outcomes of patients with sepsis
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Abstract
Objective: To determine plasma magnesium (Mg) level and to evaluate the association between plasma Mg level and outcomes of patients with sepsis. Subject and method: A prospective descriptive study was conducted on 125 patients with sepsis treated at 108 Military Central Hospital from November 2019 to February 2021. Plasma Mg levels were measured at admission (Mg1) and on day 3 after admission (Mg3), 30-day follow-up of survival and mortality. Result: In 125 patients with sepsis, the rate of Mg1 deficiency was 48.8%. The plasma Mg1 and Mg3 levels were 0.70 (0.6-0.81) mmol/L vs 0.75 (0.65-0.85) mmol/L respectively, p=0.001. SOFA score in the Mg1 deficient group was higher than in the non-deficient group (8.48 ± 4.06 vs 6.8 ± 3.92, p<0.05). Mg1 level in the shock group was lower than in the non-shock group (0.65 (0.57-0.73) mmol/L vs 0.75 (0.67-0.87) mmol/L, p<0.001). There was no statistically significant difference in plasma Mg1 levels between the mechanical ventilation and non-ventilation groups, between the renal and non-renal failure groups, between the liver failure and non-liver failure groups, and between the 30-day mortality and survival groups. Conclusion: Mg1 deficiency was common in patients with sepsis. The plasma Mg1 level was lower than the plasma Mg3 level. The Mg1-deficient group had higher SOFA scores than the non-deficient group. The septic shock group had a lower Mg1 level than the non-shock group. There was no statistically significant difference in plasma Mg1 levels between the 30-day mortality and survival groups.
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References
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