ISSN: 1859 - 2872
Evaluating prevention of postoperative vomiting, nausea and pain of pre-operative systemic dexamethasone in thyroidectomy
Main Article Content
Keywords
Abstract
Objective: To evaluate preventing postoperative pain, nausea and vomiting of pre-operative systemic dexamethasone in thyroidectomy at Anesthesia and Pain Control Center, Hanoi Medical University Hospital from July 2021 to August 2022. Subject and method: A prospective randomized controlled trial interventional study. Control Group (Group C): Don’t use dexamethasone before operation and Study Group (Group D): Using dexamethasone 8mg before operation. Result: The vomiting, nausea rate in the group using dexamethasone (23.1%) was significantly lower than in the group did not use dexamethasone (46.1%) with statistically significant difference. The vomiting, nausea level and anti-emesis request in the non-dexamethasone groups was higher than study group (Using dexamethasone). The medium VAS in 24 hours postoperative in group using dexamethasone (4.1%) was lower than control group (Non-dexamethasone) (5.8%) with statistically meaning difference, and the needs of using painkiller at second time in using dexamethasone group was lower than non-dexamethasoen group (Control Groups). Conclusion: Using dexamethasone reduce significantly ration of nausea and vomiting postoperative thyroidectomy; effect pain prevention of dexamethasone in our study is not clear and we need more data for conclusion.
Article Details
References
2. Cao X, White PF, Ma H (2017) An update on the management of postoperative nausea and vomiting. J Anesth 31(4): 617-626.
3. Chen CC, Siddiqui FJ, Chen TL et al (2012) Dexamethasone for prevention of postoperative nausea and vomiting in patients undergoing thyroidectomy: Meta-analysis of randomized controlled trials. World J Surg 36(1): 61-68.
4. Feroci F, Rettori M, Borrelli A et al (2011) Dexamethasone prophylaxis before thyroidectomy to reduce postoperative nausea, pain, and vocal dysfunction: A randomized clinical controlled trial. Head Neck 33(6): 840-846.
5. Ho CM, Wu HL, Ho ST et al (2011) Dexamethasone prevents postoperative nausea and vomiting: Benefit versus risk. Acta Anaesthesiol Taiwan 49(3): 100-104.
6. Lee Y, Lai H Y, Lin P C et al (2004) A dose ranging study of dexamethasone for preventing patient-controlled analgesia-related nausea and vomiting: A comparison of droperidol with saline. Anesth Analg 98(4): 1066-1071.
7. Song YK, Lee C (2013) Effects of ramosetron and dexamethasone on postoperative nausea, vomiting, pain, and shivering in female patients undergoing thyroid surgery. J Anesth 27(1): 29-34.
Article Sidebar
