Đặc điểm lâm sàng và một số yếu tố liên quan của hội chứng đỏ da toàn thân tại Bệnh viện Da liễu Thành phố Hồ Chí Minh từ năm 2016-2020

Abstract

Objective: To survey clinical characteristics of erythroderma at Ho Chi Minh City Hospital of Dermatology and Venereology and the trends of etiologies from 2016 to 2020. Subject and method: We designed a cross-sectional study of 412 cases of erythroderma patients during the period of 01/01/2016 to 31/12/2020, Result: The mean age was 56.58 with a male/female ratio of 4.7/1. Mean BMI was 21.79. The recurrence rate was 75.2%. Outstanding clinical features: Fever 11.1%, severe itching 67.7%, severe pain 9.2%; fatigue 2.4%, exfoliation 83.0%, leakage 29.4%, nail damage 30.3%. Blood abnormalities that were statistically different between improved and non-improved treatment outcomes include: Lymphocyte count, HCT, creatinine, SGOT, SGPT, albumin. There were 4 groups of causes of erythroderma: Pre-existing skin disease (88.35%), drugs (8.98%), cancer (1.21%) and unknown cause (1.46%). Percentage of erythroderma due to pre-existing skin diseases tended to decrease gradually, while drug-induced causes tended to increase gradually over recent years. Conclusion: Cause of pre-existing skin diseases tend to decrease over recent years. On the contrary, drug-related causes tend to increase gradually over recent years.