ISSN: 1859 - 2872
Serum level of insulin-like growth factor-1 and related factors in patients with acne vulgaris
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Abstract
Objective: To describe the clinical manifestations of patients with acne vulgaris and measure the serum level of IGF-1 and related factors in patients with acne vulgaris and compare to the normal controls. Subject and method: A cross-sectional descriptive study was conducted on 59 patients with acne vulgaris the Ho Chi Minh City Hospital of Dermato-Venereology in 2020-2021 and 30 healthy people in the control group. Result: The median age of acne patients was 17 years. The median age of onset for acne patients was 13 years. The median duration of illness was 6 months. Patients with acne vulgaris had a mean GAGS score of 20.85 ± 5.55 points. The patients with medium severity level accounted for the highest proportion with 30 patients (50.8%). The average serum level of IGF-1 in patients with acne vulgaris was 296.42 ± 71.21ng/ml. The serum level of IGF-1 in the normal group was 227.41 ± 101.86ng/ml. Conclusion: Serum level of IGF-1 in the group of patients with acne vulgaris was significantly higher than the control group (p<0.001).
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References
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