ISSN: 1859 - 2872
Investigating the status of EBV infection in gastric cancer patients in Viet Nam
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Abstract
Objective: To determine the status of EBV infection and the characteristics of EBV-positive gastric cancer. Subject and method: A cross-sectional study of 179 patients: gastric cancer (n = 89) and chronic gastritis (n = 90) with diagnosed by histopathology. EBV infection was determined by realtime-PCR. Result: The rate of EBV infection of this population was 133/179 (74.3%), of which the gastric cancer group was higher than the chronic gastritis group (80.9% versus 67.8%), the difference was statistically significant (p<0.05). Gastric cancer had the highest prevalence of EBV infection in the young age group (under 45) and was common in the cardia and body (100% and 92.9%, respectively). Conclusion: EBV infection may increase the "risk" of gastric cancer in Vietnam. EBV-positive gastric cancer is more common at young age and the tumor location is in the upper part of the stomach.
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References
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