ISSN: 1859 - 2872
The value of PAP index for prediction of esophageal varices in patients with cirrhosis
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Keywords
PAP index, esophageal varices, cirrhosis
Abstract
Objective: To evaluate PAP Index in prediction of esophageal varices (EV) in cirrhotic patients. Subject and method: A prospective, cross-sectional descriptive study carried out on 108 patients with cirrhosis at Digestive Department of 103 Military Hospital. The PAP index was calculated by using Farid’s proposed formula. Result: Prevalence of EV was 75.0%. At the cut-off value of 0.285, PAP score had 72.8% sensitivity, 77.8% specificity, 90.8% positive predictive value, 48.8% negative predictive value for predicting the presence of EV. PAP index predicted hight oesophageal varices with AUC of 0.77. Conclusion: The PAP score was the useful non-invasive measures in prediction of the presence of EV in cirrhotic patients.
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References
1. Trần Phạm Chí (2014) Nghiên cứu hiệu quả thắt giãn tĩnh mạch thực quản kết hợp propranolol trong dự phòng xuất huyết tái phát và tác động lên bệnh dạ dày tăng áp cửa do xơ gan. Luận án tiến sỹ y học, Trường Đại học Y dược Huế.
2. Trần Thị Khánh Tường, Hoàng Trọng Thảng (2012) Các phương pháp đánh giá xơ hóa gan không xâm nhập. Tạp chí Gan mật Việt Nam, 12; tr. 186-192.
3. Angeli P, Villanueva C, Francoz C et al (2018) EASL clinical practice guidelines for the management of patients with decompensated cirrhosis. J Hepatol 69: 406-460.
4. Baveno VI Faculty (2015) Expanding consensus in portal hypertension: Report of the Baveno VI consensus workshop: Stratifying risk and individualizing care for portal hypertension. J Hepatol 63: 743-752.
5. Deng H, Qi X, Peng Y et al (2015) Diagnostic accuracy of APRI, AAR, FIB-4, FI, and King Scores for diagnosis of esophageal varices in liver cirrhosis: A retrospective study. Med Sci Monit 21: 3961-3977.
6. Farid K, Omran MM, Farag RE et al (2017) Development and evaluation of a novel score for prediction of large oesophageal varices in patients with hepatitis C virus - induced liver cirrhosis. British Journal of Biomedical Science 74(3): 138-143.
7. Kraja B, Mone I, Akshija I et al (2017) Predictors of esophageal varices and first variceal bleeding in liver cirrhosis patients. World J Gastroenterol 23(26): 4806-4814.
8. Zhang F, Liu T, Gao P et al (2018) Predictive value of a noninvasive serological hepatic fibrosis scoring system in cirrhosis combined with oesophageal varices. Can J Gastroenterol Hepatol. 2018: 7671508.
2. Trần Thị Khánh Tường, Hoàng Trọng Thảng (2012) Các phương pháp đánh giá xơ hóa gan không xâm nhập. Tạp chí Gan mật Việt Nam, 12; tr. 186-192.
3. Angeli P, Villanueva C, Francoz C et al (2018) EASL clinical practice guidelines for the management of patients with decompensated cirrhosis. J Hepatol 69: 406-460.
4. Baveno VI Faculty (2015) Expanding consensus in portal hypertension: Report of the Baveno VI consensus workshop: Stratifying risk and individualizing care for portal hypertension. J Hepatol 63: 743-752.
5. Deng H, Qi X, Peng Y et al (2015) Diagnostic accuracy of APRI, AAR, FIB-4, FI, and King Scores for diagnosis of esophageal varices in liver cirrhosis: A retrospective study. Med Sci Monit 21: 3961-3977.
6. Farid K, Omran MM, Farag RE et al (2017) Development and evaluation of a novel score for prediction of large oesophageal varices in patients with hepatitis C virus - induced liver cirrhosis. British Journal of Biomedical Science 74(3): 138-143.
7. Kraja B, Mone I, Akshija I et al (2017) Predictors of esophageal varices and first variceal bleeding in liver cirrhosis patients. World J Gastroenterol 23(26): 4806-4814.
8. Zhang F, Liu T, Gao P et al (2018) Predictive value of a noninvasive serological hepatic fibrosis scoring system in cirrhosis combined with oesophageal varices. Can J Gastroenterol Hepatol. 2018: 7671508.
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How to Cite
ThinhL. D., VietN. D., & HuyD. Q. (2020). The value of PAP index for prediction of esophageal varices in patients with cirrhosis. Tạp Chí Y Dược lâm sàng 108, 15(3), 1-7. Retrieved from https://tcydls108.benhvien108.vn/index.php/YDLS/article/view/159