ISSN: 1859 - 2872
Prevalence of JCV infection in kidney transplant patients at the 108 Military Central Hospital from March 2018 to June 2022
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Abstract
Objective: To identify the prevalence of JCV infection in kidney transplant patients at the 108 Military Central Hospital. Subject and method: A longitudinal study to follow up 94 out of 114 patients who had first-time kidney transplantation at 108 Military Central Hospital. Patients followed the routine clinical examination every three months in the first-year post-transplantation (T1, T3, T6, T9, T12) and every six months in the following years (T18, T24, T30, T36, T42, T48, T60). Result: Prevalence of JCV in the kidney transplant recipients was 62 (66.0%), There was 16.0% patients had positive with JCV at T1, 16.0% at T3, 11.7% at T9, 21.2% at T12, 22 (23.4%) at T18, 23.4% at T24, 22.3% at T30, 16% at T36, 14.9% at T42, 8.5% at T48, 4.2% at T54, and 1.06% at T60. The number of JCV in T6 was highest at 30.8%, higher significantly than other times, p<0.05 (Chi-square- Test). The number of JC Viremia infections was 27/663 (4.2%), lower significant than the number of JC viruria 229/663 (34.5%). Conclusion: The incidence of JCV infection at T6 was the highest number and decreased steadily over time. The prevalence of JC viremia was notably lower than JC viruria. The monitoring for post-transplant JCV infection is recommended to be done regularly and continuously throughout post-kidney treatment.
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References
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