Change of clinical and subclinical symptoms of plasma exchange therapy in patients with hypertriglyceridemia-induced acute pancreatitis

  • Lê Xuân Dương Bệnh viện Trung ương Quân đội 108

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Keywords

Hypertriglyceridemia, acute pancreatitis, plasma exchange

Abstract

Objective: The study aimed to evaluate the effectiveness of clinical and subclinical symptoms improvement of Plasma Exchange therapy (Plasma Exchange - PEX) in Patients with hypertriglyceridemia-induced acute pancreatitis. Subject and method: A prospective study of 83 patients with hypertriglyceridemia-induced acute pancreatitis treated at Bach Mai Hospital from 2016 to 2019. Patients were examined and tested for clinical and subclinical before and after PEX. Result: Clinical and subclinical symptoms improved markedly after the first PEX: Abdominal pain (decreased from 100% to 50%), bloating (decreased from 100% to 72.3%), increased intra-abdominal pressure (decreased from 63.3% to 16.9%), heart rate (decreased from 108.2 ± 19.2 to 98.1 ± 14.7 times/minute), MAP (increased from 73.4 ± 25.1 to 80.1 ± 30.2mmHg), triglyceride (decreased by 70.8%), cholesterol (decreased by 61.6%), amylase (decreased by 56.4%), lipase (decreased by 44.4%). Conclusion: PEX improved clinical and subclinical symptoms markedly in patients with hypertriglyceridemia-induced acute pancreatitis.

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References

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