ISSN: 1859 - 2872
Initial results of concurrent chemoradiation therapy using EP for neuroendocrine carcinoma of the cervix at National Cancer Hospital
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Abstract
Objective: To study clinical characteristics and treatment response rates to concurrent chemoradiotherapy of neuroendocrine tumors of the uterine cervix (NTUC) at K Hospital from 2018 to 2020. Subject and method: Non-controlled clinical intervention study, we included patients whose tumors were described in the original pathology as NTUC, FIGO IB-IIIC, at K Hospital, from 2018-2020. Patients were treated by definitive chemoradiotherapy using EP regimen. Result: 40 patients were enrolled in the study, the mean age was 45.8, the small cell subtype accounted for the largest (80%), the rate of FIGO stage I, II, III were 17.5%, 35% and 47.5%, respectively. 30/40 patients had complete response (75%), 4/40 patients had partial response (10%) and 6/40 had progressive disease (15%). Conclusion: NTUC was rare disease with poor prognosis, the rate of advanced disease was high. Concurrent chemoradiotherapy using EP was effective for patients with NTUC, however, longer follow-up time is needed to evaluate survival outcome.
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References
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