Đánh giá tình trạng bội nhiễm vi khuẩn và mức độ đề kháng kháng sinh ở người bệnh thở máy tại Trung tâm Hồi sức tích cực, Bệnh viện Dã chiến số 13

Abstract

Objective: To evaluate the rate of bacterial surinfection in mechanically ventilated patients due to COVID-19 and antibiotic resistance in isolates at the Center of severe COVID-19 management (field hospital 13^th) in Ho Chi Minh City. Subject and method: The study was conducted in a totally new built up center of critical care during the fourth wave of COVID-19 in Ho Chi Minh city in August – October 2021. It analyzed all the positive bacterial cultures and their antibiograms. Result: 90.19% of surinfection was due to gram-negative bacteria, mostly Acinetobacter baumanii and Klebsiella pneumoniae. Among the 9.84% of surinfection due to gram positive bacteria, Enterococcus was the most common. Most of the isolated sources were multi-resistant. Conclusion: Ventilated COVID-19 patients had a high rate of superinfection with multidrug-resistant gram-negative bacteria; antibiotic resistance in the community in Vietnam was very high and needs to be strictly controlled; we recommend not to use antibiotics for COVID-19 patients without signs of surinfection to avoid the development of drug-resistant strains of bacteria and the spread of resistant strains to the community.