Diffuse idiopathic skeletal hyperostosis with ossification of posterior longitudinal ligament with neurological deficit: A case report

  • Hoàng Gia Du Bệnh viện Bạch Mai

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Keywords

Diffuse idiopathic skeletal hyperostosis, Foresier disease, ossification of posterior longitudinal ligament, case report

Abstract

Introduction: Diffuse idiopathic skeletal hyperostosis (DISH), or Forestier disease is a systemic condition characterized by calcification and ossification of ligament and enthuses in the vertebral column and peripheral skeleton, which mainly affects the anterior longitudinal ligament in the male over 50 years of age. We report a case of a younger women suffer from diffuse idiopathic skeletal hyperostosis with ossification of posterior longitudinal ligament. Thereby, review of literature on the diagnosis and treatment of DISH. Case presentation: A 33 years old woman with medical history of polymyositis and systemic lupus erythematosus diagnosed in 6 years, complaint of incremental quadriplegia and paresthesia, not responding with medical treatment. X-rays and CT scan reveal bridging ossification of anterior longitudinal (ALL) and posterior at C3-C7 vertebral segments, MRI reveal corresponing cervical spinal cord compression. Patient is diagnosed diffuse idiopathic skeletal hyperostosis with ossification of posterior longitudinal ligament at C4-C7 vertebral segments leading to cervical spinal cord compression, then patient is treated by anterior cervical corpectomy and fusion C5C6C7. Postoperatively, clinical symptoms have been improvement. Conclusion: Diffuse idiopathic skeletal hyperostosis can occur in the young women with ossification of posterior longitudinal ligament. That is a benign disease, so diagnosing and treating early is very necessary to prevent permanent myelopathy.

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References

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