ISSN: 1859 - 2872
Assessing the result of video-assisted thoracoscopic esophagectomy in squamous cell esophageal cancer with locoregional invasion
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Abstract
Objective: To evaluate the results of esophagectomy in patients with locoregional invasion. Subject and method: From March 2020 to August 2021, 17 patients with advanced stage T4a esophageal cancer evaluated intraoperatively underwent esophagectomy using substernal route. Record the characteristics of clinical, paraclinical, disease stage, complications and mortality after surgery. Overall survival was analyzed according to Kaplan-Meier. Prognostic factors were analyzed according to Cox regression model. Data were analyzed using SPSS 20.0 software. Result: 100% of patients were male with histopathological lesion of squamous cell carcinoma. 94.1% of patients received combined chemotherapy and radiotherapy. The diagnostic concordance rate for depth of invasion was 47.06%. The diagnostic concordance rate for lymph node metastasis was 23.53%. All patients used the retrosternal tunnel. The rate of R0 resection reached 94.1%. The average number of lymph nodes removed was 25.76, of which the average number of positive nodes was 1.18. The pleura was the most invaded organ. About postoperative complications: hoarseness was the most common complication. Mean follow-up time was 7.6 months. Mortality rate was 11.8%. There were no local recurrences. Mean survival time was 17.28 months. The mean survival rate at 12 months postoperatively was 71.4%. Age factors and tumor invasion status, lymph node metastasis had no predictive value for survival (p>0.05). Conclusion: Esophageal cancer stage T4a evaluated intraoperatively has a poor prognosis, however, esophagectomy is feasible and safe.
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References
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