Nghiên cứu đặc điểm lâm sàng, cận lâm sàng và đánh giá biến chứng thận ở bệnh nhân đái tháo đường típ 2 tại Khoa Nội tiết-Bệnh viện Trung ương 103 Quân đội nhân dân Lào

Abstract

Objective: To describe clinical and subclinical characteristics of patients with type 2 diabetes; Comment on the characteristics of kidney complications and the relationship with the level of blood sugar control. Subject and method: 102 type 2 diabetes patients with kidney complications treated at the Endocrinology Department of the 103 Central Hospital of the Lao People's Army from June 2020 to December 2021. Method: A cross-sectional description. Result: People over 50 years old accounted for 94.2%, more women than men (61.8% and 38.2%). Only 23.7% of patients adhered to diet and exercise. Patients with type 2 diabetes with comorbid hypertension accounted for 57.8%. The number of patients with good control of fasting blood sugar accounted for 30.1%, good control of blood sugar at any time accounted for 19.4%, and good control of HbA1C was 38.3%. Renal complications: 42.2% of patients had proteinuria. In 57.8% of patients with negative proteinuria, 10.8% had positive MAU and 47% had negative MAU. The proportion of patients with diabetic kidney disease stage 3, 4, and 5 were 9.8%, 20.6%, and 22.5%, respectively. Patients with type 2 diabetes with hypertension had a risk of kidney complications 2.57 times higher than those without hypertension (p<0.05). Patients with type 2 diabetes with poor fasting glucose control were 3.04 times more likely to develop stage 3 + 4 diabetic nephropathies than those with well controlled fasting glucose (p<0.05). Patients with type 2 diabetes with uncontrolled HbA1c were 3.57 times more likely to develop stage 3 + 4 diabetic nephropathies than those with well controlled HbA1c (p<0.05).