Effectiveness of polyurethane gauze in Lyell’s syndrome

  • Lê Thị Lài Tâm 108 Military Central Hospital
  • Nguyễn Thị Hải Yến 108 Military Central Hospital
  • Hoàng Thị Hà 108 Military Central Hospital
  • Lê Phương Anh 108 Military Central Hospital
  • Cù Kim Chung 108 Military Central Hospital
  • Nguyễn Hồng Hạnh 108 Military Central Hospital
  • Nguyễn Thị Thắm 108 Military Central Hospital

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Keywords

Lyell’s syndrome, polyurethane gauze

Abstract

Lyell’s syndrome, which can be called Toxic epidermal necrolysis-TEN, is a serious reaction of the skin and mucous membranes with the necrolysis and loss of the epidermal layer. The most common cause is medicine. The prognosis of Lyell is severe, the death rate is more than 30%, usually because of infection, especially the sepsis, erythrolyte disorder, disfunction of organ: Hepatic, kidney. Topical wound care is essential in the treatment of TEN to ensure that lesion not spreading, to prevent infection, to reduce pain, and to aid in wound healing. We report a case with a confirmed diagnosis of Lyell's syndrome, with a plan to treat and care for skin lesions with Polyurethane gauze, after 25 days of treatment, the patient was discharged from the hospital and left no complication.

Article Details

References

1. Cát Vân Anh, Nguyễn Văn Đoàn (2012) Triệu chứng lâm sàng và tổn thương kết mạc trên bệnh nhân dị ứng thuốc. Tạp chí Nghiên cứu Y học 80(3), tr. 113-118.
2. Nguyễn Quốc Anh, Ngô Quý Châu (2011) Hướng dẫn chẩn đoán và điều trị bệnh nội khoa. Nhà xuất bản Y học, tr. 771-773.
3. Bộ Y tế (2016) Dị ứng thuốc. Hướng dẫn chẩn đoán và điều trị các bệnh về dị ứng - miễn dịch lâm sàng. Nhà xuất bản Y học, tr .17-29.
4. Nguyễn Văn Đoàn (2011) Dị ứng thuốc. Nhà xuất bản Y học, tr. 203-207.
5. Mockenhaupt M, Viboud C, Dunant A (2008) Stevens-johnson syndrome and toxic epidermal necrolysis: Assessment of medication risks with emphasis on recently marketed drugs. the euroscar-study. Journal of Investigative Dermatology 128: 35-44.
6. Sahar K, Palioura S, Saeed HN et al (2016) Stevens-Johnson Syndrome/Toxic epidermal necrolysis a comprehensive review and guide to therapy. I. Systemic Disease. Ocul Surf 14(1): 2-19.
7. Dirk T Ubbink, Hester Vemeulen RN (2008) Occlusive vs gauze dressing for local wound care in surgical patients: A randomized clinical trial. Arch surg 143(10): 950-955.
8. Guest JF, Ruiz F (2005) Modelling the cost implications of using carboxymethylcellulose dressing with gauze in the management of surgical wounds healing by secondry intention in the US and UK. Curr med res opin 21(2) 281-290.
9. Robinson BJ (2009) The use of a hydrofibre dressing in wound management. J wound care 9 (1): 32-34.