Đặc điểm tổn thương gan ở bệnh nhân COVID-19 mức độ nặng và nguy kịch tại Bệnh viện Dã chiến Truyền nhiễm 5G

Abstract

Objective: To describle liver injury in severe and critical COVID-19 patients, who were treated in Infectious Field Hospital No.5G. To find out the relationship between liver injury and the mortality. Subject and method: A respective cohort study on 156 severe and critical COVID-19 patients at ICU of Infectious Field Hospital No.5G- Hochiminh city from August to November 2021. Result: There were 92.9% of the patients had liver injury, 46.8% of these were mild level. The severe COVID-19 group had lower average of ALT, AST, GGT, total bilirubin, direct bilirubin, prothrombin and higher average of albumin than the critical COVID-19 group. The mortality rate gradually increased from the group without liver injury to the group of mild, moderate and severe liver injury (54.5%, 76.7%, 84.2% and 91.2%). This difference was statistically significant (p=0.0067). Conclusion: Most of the patients had liver injury and the majority of them were mild level. The critical COVID-19 group had more serious liver injury than the severe COVID-19 group. The more severe liver damaged, the higher mortality rate increased.