Tổn thương thân não cấp tính trong rối loạn phổ viêm tuỷ thị thần kinh: Báo cáo chùm trường hợp lâm sàng và điểm y văn

Abstract

Neuromyelitis Optica Spectrum Disorder (NMOSD) is a severe, antibody- mediated central nervous system inflammatory demyelinating disorder, characterized by acute myelitis and optic neuritis. A major advance was the discovery of the highly specific the antibodies target the water channel aquaporin-4 (AQP4-immunoglobulin G, AQP4-IgG) in serum of the patients clinically diagnosed NMO. The specificity of AQP4-IgG further broadened the clinical spectrum of NMO, with the identification of seropositive patients with atypical presentations, included the symptoms reflect brainstem lesions. In Vietnam until now, there hadn’t been any report mentioning brainstem lesions in NMOSD. We presented a 3-case serie of the patients with brainstem lesions diagnosed with NMOSD treated at the Nerology Department, 108 Military Central Hospital.