Sự thay đổi và mối liên quan của nồng độ CRP huyết tương với biến chứng, tử vong sau phẫu thuật điều trị gãy đầu trên xương đùi ở người cao tuổi

Abstract

Ojective: To evaluate the kinetics and relationship of CRP serum to the complication, mortality after surgery proximal femur fracture in elderly patients. Subject and method: 89 patients with the age more than 60 years old operated for fracture of proximal femur between April 2020 and January 2021 at the Department Joint Surgery-Centre Trauma and Prthropaedic-103 Military Hospital. Result: CRP values increased rapidly after surgery, the peak on 2 days postoperative was 82.07± 44.0mg/l, then declined to plateau and same preoperative on 7 days postoperative. CRP level on 3 days postoperative was the most important to predict complications after surgery with area under curve was 0.761 (p=0.003), cut off point 89.3mg/l, Se 76.9%, Sp 73.0%. CRP level on 7 days postoperative was the most important to predict mortality after surgery, area under curve were 0.763 (p=0.049), cut off point 71.71mg/l, Se 60%, Sp 85.4%. Conclusion: The serum CRP value increased rapidly after surgery, reached peak on 2 days postoperative, then gradually decreasing until the 7 days postoperative to the same value before surgery. Serum CRP level had predicting value of complication and mortality after proximal femur fracture surgery in elderly patients.