Đặc điểm hình ảnh siêu âm hạch di căn trên bênh nhân ung thư tuyến giáp thể biệt hóa sau phẫu thuật cắt toàn bộ tuyến giáp

Abstract

Objective:  To evaluate the diagnostic accuracy of ultrasonography (US) in detecting cervical neck lymph node metastasis (LNM) in patients with differentiated thyroid cancer (DTC). Subject and method: From September 2019 to February 2022, a total of 604 Lymph Nodes (LNs) from 301 enrolled DTC patients (63 men, 238 women; mean age: 47.4 ± 14.8 years; range: 16-84 years) were evaluated. According to the pathologic results, 405 LNs were metastatic, and 199 LNs were benign. US was performed with a 4-18 MHz linear transducer. The US criteria for LNM were as follows: Absence of hilum, irregular edge, focal or diffuse hyperechogenicity; microcalcification; cystic change; abnormal vascular pattern (a chaotic or peripheral vascular pattern); short axis > 5mm, and transverse/long diameter ratio > 0.5. Result: Diagnostic value of US signs for the detection of cervical metastatic lymph nodes from DTC, suspicious for malignancy (at least one sign), sensitivity 96.5%, specificity 43.7%, accuracy 79.1%, (at least two signs), sensitivity 85.7%, specificity 63.8%, accuracy 78.5%, and (at least three signs) sensitivity 76.5%, specificity 81.4%, accuracy 78.1%. Conclusion: High-quality ultrasonography is an established diagnostic tool for detecting detection of local-regional metastatic disease in patients with thyroid cancer.