ISSN: 1859 - 2872
Evaluating dyslipidemia and association between lipid and 24-hour proteinuria in patients with chronic kidney disease
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Abstract
Objective: To evaluate dyslipidemia status and the relation between 24-hour proteinuria and dyslipidemia in patients with chronic kidney disease (CKD) at 108 Military Central Hospittal in 2022. Subject and method: A cross-sectional study was conducted on 102 over-18-years old patients with CKD, eGFR < 30ml/min/1.73m2 at 108 Military Central Hospittal from July, 2021 to May, 2022. A control group was 50 healthy persons. Data was collected at the time of hospitalization through face-to-face interviews and medical records. The tests were conducted at the Department of Biochemistry as soon as the hospitalization of patients. Result: There was a difference with p<0.05 in triglycerides and HDL-C levels and a difference with p>0.05 in cholesterol and LDL-C between the 2 study groups. There were positive regression between triglyceride (p=0.0001; r = 0.46) and cholesterol (p=0.0001; r = 0.37), and negative regression between HDL-C (p=0.001, r = -0.33) with 24-hour proteinuria. There was no regression between LDL-C with 24-hour proteinuria. Conclusion: The level of triglyceride was increased and HDL-C decreased significantly, cholesterol and LDL-C levels not changed significantly in CKD patients. The triglyceride and cholesterol levels regressed positively and HDL-C levels regressed negatively to 24-hour proteinuria, and LDL-C did not regress to 24-hour proteinuria in CKD patients.
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References
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