Evaluation of the effectiveness of chronic urticaria treatment with 10mg oral dose of levocetirizine

  • Nguyen Hoang Van 103 Military Hospital
  • Nguyễn Phú Cường Học viện Quân y
  • Bùi Thị Vân Bệnh viện Trung ương Quân đội 108

Main Article Content

Keywords

Chronic urticaria, Anti-H1 histamine

Abstract

Objective: Evaluation of the effectiveness of chronic urticaria treatment with a 10mg oral dose of levocetirizine. Subject and method: A clinical trial, self-compared before and after treatment on 40 chronic urticaria patients examined at the Dermatology out-patient clinic of 103 Military Hospital from September 2021 to June 2022. Patients were treated with a 10mg oral dose of levocetirizine daily for four weeks. Urticaria activity score and quality of life score were recorded weekly. Result: The mean chronic urticaria patient's age was 42.27 ± 15.37. After 4 weeks of treatment, the UAS index decreased from 4.58 ± 1.01 at the beginning of treatment to 1.33 ± 1.33 at the end of therapy. The quality of life improved markedly more than those at the beginning of treatment, with a mean score of 31.50 ± 8.82. Forty-five percent of chronic urticaria patients had excellent response without symptoms after 4 weeks treated with a 10mg dose of levocetirizine therapy. The most common side effect was sedation (12.5%). Conclusion: 10mg oral levocetirizine therapy effectively controls symptoms of chronic urticaria.

Article Details

References

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