ISSN: 1859 - 2872
Generalized pustular psoriasis exacerbated by vaccination against severe acute respiratory syndrome by coronavirus 2: A case report
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Keywords
COVID-19, COVID-19 vaccin, mARN, generalized pustular psoriasis, mARN (messenger ARN)
Abstract
Generalized pustular psoriasis (GPP) is a rare but potentially - life threatening variant of psoriasis vulgaris, with many possible triggers, including medication, infections. However, vaccines have rarely been reported to exacerbate GPP. Herein, we describle, based on our observations and a literature review, we report the case of GPP following the COVID-19 messenger RNA (mARN) vaccine. This is the first psoriasis patient who developed the generalized pustular psoriasis flare after the second dose of COVID-19 vaccine we clinically encountered.
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References
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2. Elamin S, Hinds F and Tolland J (2022) De novo generalized pustular psoriasis following Oxford-AstraZeneca COVID-19 vaccine. Clin Exp Dermatol 47(1): 153-155.
3. Farkas A, Tonel G, Nestle FO (2008) Interferon-alpha and viral triggers promote functional maturation of human monocyte-derived dendritic cells. Br J Dermatol 158(5): 921-929.
4. Hoegler KM, John AM, Handler MZ, Schwartz RA, (2018) Generalized pustular psoriasis: a review and update on treatment. J Eur Acad Dermatol Venereol 32(10): 1645-1651.
5. Lin Y, Slight SR and Khader SA (2010) Th17 cytokines and vaccine-induced immunity. Semin Immunopathol 32(1): 79-90.
6. Onsun N et al (2021) A generalized pustular psoriasis flare after CoronaVac COVID-19 vaccination: Case report. Health Promot Perspect 11(2): 261-262.
7. Perna D, Jones J and Schadt CR (2021) Acute generalized pustular psoriasis exacerbated by the COVID-19 vaccine. JAAD Case Rep 17: 1-3.
8. Sbidian E et al (2014) National survey of psoriasis flares after 2009 monovalent H1N1/seasonal vaccines. Dermatology 229(2): 130-135.
9. Takahashi H et al (2011) Analysis of psoriasis patients registered with the Japanese Society for Psoriasis Research from 2002-2008. J Dermatol 38(12): 125-129.
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Published
Aug 8, 2022
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Articles
How to Cite
Ngọc ViL., Lan AnhN., Quỳnh TrangN., Thu TrangV., Phương LinhB., & Thanh HàN. (2022). Generalized pustular psoriasis exacerbated by vaccination against severe acute respiratory syndrome by coronavirus 2: A case report. Tạp Chí Y Dược lâm sàng 108, 17(5). https://doi.org/10.52389/ydls.v17i5.1364