Characteristics of nosocomial infections and related factors at Vinh Phuc Hospital's Intensive Care Unit from January to September 2021

  • Nguyễn Đức Quỳnh Bệnh viện Đa khoa tỉnh Vĩnh Phúc
  • Dương Thị Thanh Mai Bệnh viện Đa khoa tỉnh Vĩnh Phúc
  • Bùi Minh Thi Bệnh viện Đa khoa tỉnh Vĩnh Phúc
  • Khổng Thị Ngọc Huyền Bệnh viện Đa khoa tỉnh Vĩnh Phúc

Main Article Content

Keywords

Mosocomial infections, ventilator-associated pneumonia, risk factors

Abstract

Objective: To investigate the rate of multiple types of nosocomial infections and related factors at Department of Intensive Care, Vinh Phuc province Hospital. Subject and method: This was a prospective, cross-sectional study on 280 patients treated for more than 48 hours at the Intensive Care Unit (ICU) of Vinh Phuc Province Hospital from January to September 2021. Result: The rate of nosocomial infections was 31.1% with an incidence rate of 25.1/1000 days of hospital stay, ventilator-associated pneumonia (VAP) was the most common 32.2% with 42.3/1000 days of mechanical ventilation (DU = 0.4) followed by catheter-associated urinary tract infection (CAUTI) accounted for 10% with 10.7/1000 days of urinary catheter retention (DU = 0.6). The most common agent causing nosocomial infections was A. baumannii (34.4%). The three strongest risk factors for increasing the likelihood of UTI in multivariable analysis were mechanical ventilation (OR = 4.45, 95%CI: 1.68-11.7, p<0.05), blood transfusion (OR = 2.12, 95%CI:
1.0-4.5, p<0.05), hospital stay > 7 days (OR = 25, 95%CI: 5.49-85.5, p<0.001. Conclusion: The rate of nosocomial infections in the Department of Intensive Care was high (31.1%) in which VAP accounts for the highest rate (32.2%), the most common agent A. baumannii. Prolonged hospital stay with device use, surgical interventions increases the risk of nosocomial infections.

Article Details

References

1. Ahmet Yardım et al (2021) The relationship between mortality and Hospital-Acquired infections in patients followed-up with neurological complaints in the third level Intensive Care Unit. New Trend Med Sci 2(1): 24-30.
2. Nguyen Thi Thu Hoai, Nguyen Ngoc Thuy Giang, Huynh Van An (2020) Hospital-acquired infections in ageing Vietnamese population: Current situation and solution. MedPharmRes 4(2): 1-10. doi:10.32895/ ump.mpr.4.2.1
3. Trần Văn Quang (2019) Nghiên cứu tình hình nhiễm khuẩn bệnh viện và các yếu tố liên quan tại Bệnh viện đa khoa tỉnh Vĩnh Phúc năm 2019. Đề tài cấp cơ sở.
4. CDC (2019) HAI Data and Statistics. CDC's National Healthcare Safety Network (NHSN).
5. Lê Sơn Việt (2020) Đánh giá tình hình nhiễm khuẩn tại Khoa Hồi sức tích cực - Bệnh viện Bạch Mai. Luận văn thạc sỹ Y học.
6. Despotovic A, Milosevic B, Milosevic I et al (2020) Hospital-acquired infections in the adult intensive care unit-Epidemiology, antimicrobial resistance patterns, and risk factors for acquisition and mortality. American journal of infection control 48(10): 1211-1215.
7. Abulhasan YB, Abdullah AA, Shetty SA (2020). Health care-associated infections in a neurocritical care unit of a developing country. Neurocritical care. 32(3): 836-846. doi:10.1007/ s12028-019-00856-8
8. Migliara G, Di Paolo C, Barbato D et al (2019) Multimodal surveillance of healthcare associated infections in an intensive care unit of a large teaching hospital. Annali di igiene: Medicina preventiva e di comunita 31(5): 399-413. doi:10. 7416/ai.2019.2302
9. Kolpa M, Walaszek M, Gniadek A, Wolak Z, Dobro (2018) Microbiological profile and risk factors of healthcare-associated infections in intensive care Units: A 10 year observation in a provincial hospital in southern poland. International journal of environmental research and public health.
10. Labi AK, Obeng-Nkrumah N, Owusu E et al (2019) Multi-centre point-prevalence survey of hospital-acquired infections in Ghana. The Journal of hospital infection 101(1): 60-68. doi:10.1016/ j.jhin.2018.04.019.