ISSN: 1859 - 2872
Assessment for glucose tolerance postpartum and relative with some factors in women with gestational diabetes
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Abstract
Objective: To evaluate prevalence 6 weeks postpartum diabetes and relative with some factors in women with gestational diabetes Subject and method: A cross-sectional and follow up to 6 weeks postpartum on 93 pregnant women with GDM from 7/2018 to 7/2019 at National Hospital of Endocrinology. All women was scheduled for OGTT 75g at 6 weeks postpartum. The diagnosis type 2 diabetes mellitus based on the WHO criteria 2006. Result: Prevalence type 2 diabetes 6 weeks postpartum was 11.8%; prediabetes 47.3%, normal glucose tolerance 40.9%. BMI pre-pregnancy ≥ 23kg/m2 increased risk type 2 diabetes postpartum 8.27 fold. Optimal glycemic control in pregnancy reduced risk type 2 diabetes (OR = 0.1, p<0.05). BMI pre-pregnancy level 22.2kg/m2 predict postpartum type 2 diabetes mellitus with highest sensitve (90.9%) and specificity (70.7%), AUC = 0.803 (p=0.002). BMI pre-pregnancy ≥ 22.2kg/m2 increased risk type 2 diabetes postpartum 6.95 fold (p<0.01). BMI at diagnosed gestational diabetes ≥ 25.2kg/m2 increase risk of type 2 diabetes postpartum 5.21 fold (p<0.05). Conclusion: Prevalence 6 weeks postpartum diabetes is 11.8%. Overweight/obesity pre-pregnancy increased risk type 2 diabetes postpartum. BMI pre-pregnancy level 22.2kg/m2 predict type 2 diabetes mellitus with highest sensitve and specificity. BMI pre-pregnancy ≥ 22.2kg/m2 and BMI at diagnosed gestational diabetes ≥ 25.2kg/m2 increased risk type 2 diabetes postpartum.
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References
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