Bước đầu nghiên cứu giá trị của thang điểm ABCR và ART trong tiên lượng thời gian sống thêm ở bệnh nhân ung thư biểu mô tế bào gan điều trị bằng phương pháp nút mạch hoá chất tại Bệnh viện Đại học Y Hà Nội

Abstract

Objective: To validate of ABCR and ART scores for predicting overall survival of hepatocellular carcinoma patients treated by conventional transarterial chemoembolization at Ha Noi Medical University Hospital. Subject and method: From January 2018 to December 2020, 30 consecutive HCC patients, mainly with the viral-induced disease, were treated with TACE. Using a regression model on the predictive variables of our population, we validated two scores designed to help for predicting overall survival. Result: In the multivariate analysis, three prognostic factors were associated with overall survival: BCLC and AFP (> 200ng/ml) at baseline and absence of radiological response. These factors were included in a score (ABCR, ranging from -3 to +6) which correlates with survival and identifies three groups. The ABCR score was validated and proved to perform better than the ART score in distinguishing between patients' prognoses. Conclusion: The ABCR and ART scores are simple and clinically relevant indexes, summing several prognostic variables endorsed in HCC. An ABCR score ≥ of 4 and ART ≥ of 1.5 before the second TACE identify patients with dismal prognosis who may not benefit from further TACE.