Outcomes of liver resection for hepatocellular carcinoma at Can Tho Central General Hospital
Main Article Content
Keywords
Abstract
Hepatectomy is a radical treatments for hepatocellular carcinoma (HCC) in the early or intermediate stages, well-preserved liver function, and good health status. Objective: To evaluate the outcomes of hepatectomy for HCC, the complication rate, overall survival time, and related factors. Subject and method: This was a research of 50 patients who underwent hepatectomy at Can Tho Central General Hospital, during the period between January 2017 and July 2020. Result: The average age was 60.76 years and the male/female ratio was 2/1; the majority of patients hospitalized due to abdominal pain accounted for 72%. The patients who had positive HBsAg and anti-HCV were 68% and 36%, respectively; Almost patients had the well-preserved liver function with Child-Pugh A 92%. Postoperative mortality and morbidity were 2% and 18%, respectively. The 1-year and 2-year survival time after surgery were 86% and 72%, respectively. There was significant correlation between the liver function and the overall survival time. Conclusion: Nowdays liver resection for hepatocellular carcinoma are remarkably effective with controllable postoperative mortality and complications. Surgical therapy for hepatocellular carcinoma gives good chance for HCC patients to survival.
Article Details
References
2. Nguyễn Đình Song Huy và cộng sự (2016) Phẫu thuật cắt gan điều trị ung thư biểu mô tế bào gan tại Khoa U gan - Bệnh viện Chợ Rẫy 2010-2015. Tạp chí Y Dược lâm sàng 108, 11 (đặc biệt), tr. 82-88.
3. Trần Công Duy Long (2013) Ứng dụng kỹ thuật tiếp cận cuống Glisson trong cắt gan điều trị ung thư tế bào gan. Hội nghị ngoại khoa toàn quốc, tr. 105-106.
4. Nguyễn Quang Nghĩa (2012) Nghiên cứu áp dụng đo thể tích gan bằng chụp cắt lớp vi tính trong chỉ định, điều trị phẫu thuật ung thư gan nguyên phát. Luận án Tiến sỹ Y học, Học viện Quân Y, Hà Nội.
5. Vũ Văn Quang (2018) Nghiên cứu ứng dụng kỹ thuật kiểm soát cuống glisson theo takasaki trong cắt gan điều trị ung thư biểu mô tế bào gan tại Bệnh viện Trung ương Quân đội 108. Luận văn tiến sĩ y học, Viện Nghiên cứu Khoa học Y dược lâm sàng 108, Bộ Quốc phòng.
6. Lê Văn Thành, Nguyễn Đại Bình (2010) Đánh giá kết quả phẫu thuật cắt gan trong ung thư biểu mô tế bào gan tại Bệnh viện K. Y Học TP Hồ Chí Minh, Tập 14 (Phụ bản của Số 4).
7. Balzan S, Belghiti J (2005) The "50-50 criteria" on postoperative day 5: An accurate predictor of liver failure and death after hepatectomy. Ann Surg 242: 824-828.
8. Cosenza CA, Hoffman AL, Podesta LG et al (1995) Hepatic resection for malignacy in the elderly. AnnSurg 61: 889-895.
9. F Charles Brunicardi, Dana K Anderson, Billiar T R, (2018) Schwartz’s principles of surgery. Mc Brown Hill Education: 1376-1377.
10. Hu JX, Dai WD, Miao XY (2009) Anatomic resection of segment VIII of liver for hepatocellular carcinoma in cirrhotic patients based on an intrahepatic Glissonian approach. Surgery 146(5): 854-860.
11. Marrero JA, Kulik LM, Sirlin CB, Zhu AX, Finn RS, Abecassis MM, Roberts LR, Heimbach JK (2018) Diagnosis, staging, and management of hepatocellular carcinoma: 2018 practice guidance by the American Association for the study of liver diseases. Hepatology 68(2): 735.
12. Omata M, Cheng AL, Kokudo N et al (2017) Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: A 2017 update. Hepatol Int 11: 317-370.
13. Okuda K, Peter RL, JW S (1984) Gross Anatomic features of the hepatocellular carcinoma from three disparate geographic areas, proposal of the New Classcification. Cancer 54 (10): 2164-2173.
14. Song-Huy Nguyen-Dinh, Albert Do, Trang Ngoc Doan Pham et al (2018 Jan 27) High burden of hepatocellular carcinoma and viral hepatitis in Southern and Central Vietnam: Experience of a large tertiary referral center, 2010 to 2016. World J Hepatol 10(1): 116-123.
15. Steven A Curley, Carlton C Barnett, Abdalla E K, (2018) Surgical management of potentially resectable hepatocellular carcinoma. https://wwwuptodatecom.
16. Urata K, Kawasaki S, Matsunami H, Hashikura Y, et al (1995) Calculation of child and adult standard liver volume for liver transplantation. Hepatology 21(5): 1317-1321.
17. Yamamoto M, Terasaki K et al (2001) Effectiveness of systematized hepatectomy with Glisson’s pedicle transection at hepatic hilus for small nodular hepatocellular carcinoma: Retrospective analysis. Surgery 130: 443-448.