ISSN: 1859 - 2872
Primary hepatic neuroendocrine carcinoma: A rare case report diagnosed after hepatectomy
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Abstract
Primary hepatic neuroendocrine carcinoma is an extremely rare tumor and difficult to differenciate with other hepatic tumors, such as cholangiocarcinoma, hepatocellular carcinoma and other focal hepatic lesions, based on diagnostic imaging results. A 66-year-old woman was referred for evaluation of hepatic mass discovered on incidentally abdominal ultrasound. The findings from computed tomography led to a diagnosis of hepatocellular carcinoma while magnetic resonance imaging results suggested of fibrolamellar hepatocellular carcinoma or focal nodular hyperplasia. A central hepatectomy was performed and the tumor was completely removed. Pathology diagnosed a malignant neoplasm of unknown type and immunohistochemistry confirmed a grade 2 neuroendocrine tumor. Non-hepatic original lesions were not found. This case highlights that the diagnosis of primary hepatic neuroendocrine carcinoma stills a challenge which needs to distinguish from other focal liver lesions, as well as, differentiate from a secondary metastatic neuroendocrine tumor.
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References
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