Some factors associated with sarcopenia among diabetic older patients

  • Nguyễn Trung Anh Bệnh viện Lão khoa Trung ương,Trường Đại học Y Hà Nội
  • Nguyễn Ngọc Tâm Bệnh viện Lão khoa Trung ương,Trường Đại học Y Hà Nội
  • Vũ Thị Thanh Huyền Bệnh viện Lão khoa Trung ương,Trường Đại học Y Hà Nội

Main Article Content

Keywords

Diabetes, sarcopenia, glucose control

Abstract

Objective: To investigate some factors associated with sarcopenia among diabetic older patients. Subject and method: A cross-sectional study was conducted in National Geriatrics Hospital in older patients. Diabetes control was classified by using blood glucose and HbA1c levels. Sarcopenia was defined by FNIH criteria. Three components of sarcopenia included muscle mass adjusted by body mass index, hand grip strength and walking speed. Result: Patients aged > 70 years old was related with 2.22 folds for having sarcopenia than that in 60 - 69 group. Male was associated with higher risk for sarcopenia than female (OR: 7.30). Diabetic patients having BMI < 18.5kg/m2 had higher odd for having sarcopenia than that in normal BMI (18.5 - 22.9kg/m2) group (OR = 2.47). Patients with poor glycemic control (fasting blood glucose > 10.0mmol/l) or acceptable blood sugar control (blood glucose: 7.2 - 10.0mmol/l) were associated with increased risk of sarcopenia than patients having good glycemic control (OR = 5.78, 95%CI= 2.26 - 14.77 and OR = 2.55, 95%CI = 1.15 - 5.61, respectively). Patients with HbA1c > 7.5% were associated with a higher risk of sarcopenia than patients with HbA1c ≤ 7.5% (OR = 2.30; 95%CI =1.32 - 4.00). Conclusion: The proportion of sarcopenia among older patients with diabetes was 51.5%. Some factors associated with higher risk for sarcopenia were advanced age (> 70 years old), male, low BMI < 18.5kg/m2, fasting plasma glucose > 10.0mmol/l and HbA1c > 7.5%.

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References

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