A case report: Early detection and monitoring of non-symptomatic recurrent metastasis of a nasopharyngeal carcinoma patient using the ultrasensitive realtime PCR assay of cell-free Epstein-Barr virus DNA

  • Le Thi Thuy Vietnam Military Medical University

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Abstract

A case report: Early detection and monitoring of non-symptomatic recurrent metastasis of a nasopharyngeal carcinoma patient using the ultrasensitive realtime PCR assay of cell-free Epstein-Barr virus DNA

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References

1. Zhang L et al (2013) Emerging treatment options for nasopharyngeal carcinoma. Drug Des Devel Ther 7: 37-52.
2. Leach BI et al (2013) Breast metastasis from nasopharyngeal carcinoma: A case report and review of the literature. Oncol Lett 5(6): 1859-1861.
3. Tabuchi K et al (2011) Early detection of nasopharyngeal carcinoma. Int J Otolaryngol 2011: 638058.
4. Kanakry J, Ambinder R (2015) The biology and clinical utility of EBV monitoring in blood. Curr Top Microbiol Immunol. 391: 475-499.
5. Zhao FP et al (2015) Levels of plasma Epstein-Barr virus DNA prior and subsequent to treatment predicts the prognosis of nasopharyngeal carcinoma. Oncol Lett 10(5): 2888-2894.
6. Huu Tho Ho, N.Q.A.V et al (2017) Establishment of ultrasensitive PCR assay targeting cell-free EBV DNA for early detection of nasopharyngeal carcinoma.
7. Shanmugaratnam K and L.H. Sobin (1993) The World Health Organization histological classification of tumours of the upper respiratory tract and ear. A commentary on the second edition. Cancer 71(8): 2689-2697.
8. Mutirangura A et al (1998) Epstein-Barr viral DNA in serum of patients with nasopharyngeal carcinoma. Clin Cancer Res 4(3): 665-669.
9. Leung SF et al (2004) Improved accuracy of detection of nasopharyngeal carcinoma by combined application of circulating Epstein-Barr virus DNA and anti-Epstein-Barr viral capsid antigen IgA antibody. Clin Chem 50(2): 339-345.
10. Lo YM et al (1999) Quantitative analysis of cell-free Epstein-Barr virus DNA in plasma of patients with nasopharyngeal carcinoma. Cancer Res 59(6): 1188-1191.