Nghiên cứu đặc điểm một số chỉ số hồng cầu và hồng cầu lưới máu ngoại vi ở bệnh nhân bệnh thận mạn tính giai đoạn cuối tại Bệnh viện Trung ương Quân đội 108

Abstract

Objective: To evaluate the characteristics of red blood cell and some reticulocyte indices performed on XN-2000 in patients with chronic kidney failure from stages III to V who have not received renal replacement therapy. Subject and method: A cross-sectional descriptive study on 41 patients with chronic kidney failure from stages III to V who have not received renal replacement therapy and treated at Endodialysis and Dialysis Department, 108 Military Central Hospital from August 2020 to November 2021. Result: Average protein and albumin concentrations were decreased when compared to normal people range. Average iron and ferritin plasma levels were within normal limits. Anemia was found in 92.68% patients, of which small red blood cells were accounted for 12.20%, hypochromic was 26.83%. Mean value of RET % was 2.14 ± 0.77%, RET# was 0.07 ± 0.03T/L and RET-He was 30.57 ± 3.78pg. The normal and reduced reticulocytes percentage were accounted for the majority, of which reduced reticulocytes account for 31.7%.​​ There were no statistically significant difference in some reticulocyte indices between male and female patients (p>0.05). There was a moderate positive correlation between Ret-He and iron plasma (r = 0.577, p<0.0010) and ferritin plasma (r = 0.511, p<0.01). Conclusion: Anemia is a common manifestation, mainly isochromic anemia. The reticulocyte indices in patients with chronic renal failure in the study were moderately positively correlated with iron and ferritin plasma.