Clinical and paraclinical features of hepatocellular carcinoma in young patients
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Abstract
Objective: The aims of the study were to describe the clinical and laboratorial features and the correlation between AFP levels and tumor number and diameter of hepatocellular carcinoma (HCC) in young adults. Subject and method: Patients diagnosed with HCC at the age of less than 40 years were collected of age, sex, hepatitis B, C virus infection status, liver function, sizes and numbers of tumors, and AFP levels. This was a descriptive study on 48 patients admitted at Bach Mai Hospital from January 2017 to December 2021. Result: Our study group included 37 male and 11 female patients (mean 34.4 years old); 42/48 patients were over 30 years old (87.8%); 43/48 (89.6%) patients with hepatitis B virus and 43/48 (89.6%) patients with good liver function (Child-Pugh A/B). There was an insignificant correlation between AFP levels and the numbers and size groups of tumors. Conclusion: Early-onset HCC was observed in young people with obvious risk factors for hepatitis B infection. It is necessary to closely monitor the group of subjects with chronic hepatitis B virus for early detection of HCC.
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References
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