Surgical midterm outcomes of arterial switch operation for neonate transposition of the great arteries-intact ventricular septum at VietNam National Children’s Hospital

  • Nguyen Ly Thinh Truong VietNam National Children’s Hospital
  • Nguyen Tuan Mai VietNam National Children’s Hospital

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Keywords

Transposition of the great arteries, arterial switch operation, intact ventricular septum, neonatal

Abstract

Objective: To evaluate the midterm outcomes of arterial switch operation for neonate patients with transposition of the great arteries and intact ventricular septum at Vietnam National Children’s Hospital. Subject and method: A retrospective study was conducted for all neonate patients, who underwent arterial switch operation, diagnosed with transposition of the great arteries-intact ventricular septum at Vietnam National Children’s Hospital from March 2010 to December 2016. Result: There were a total of 101 neonate patients were retrospectively studied. The mean age and the mean weight at the operation were 19.15 ± 6.92 days (1 - 30) and 3.34 ± 0.47kg (2.1 - 4.7), respectively. 6 patients (5.9%) died in-hospital and 2 (2%) late death during follow-up. The mean time of ventilation post-operative and the mean time for hospital stay after operation were 112.90 ± 118.93hours (18 - 1056) and 21.22 ± 13.01days (1 - 104), respectively. There were 43 patients who required delayed sternal closure, 4 patients have low cardiac output syndrome, and 1 patient required ECMO support after arterial switch operation. There was no reoperation during follow-up with a mean follow-up time was 19.89 ± 15.74 months (1 - 66). The Kaplan-Meier shows the survival after arterial switch operation for neonate with transposition of the great arteries and intact ventricular septum was 92%, 88.5% and 88.5% at 1 year, 5 years, and 8 years follow-up, respectively. Conclusion: Midterm outcomes of arterial switch operation for neonatal transposition of the great arteries and intact ventricular septum at Vietnam National Children’s Hospital were safe and comparable with other centers in the developed country. Further investigation with a bigger number of patients and a longer follow-up is essential.

Article Details

References

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