Assessment of the results of treating periodontitis in patients with stage 5 chronic kidney disease on maintenance hemodialysis

  • Tran Thu Giang 103 Military Medical Hospital, Military Medical Academy
  • Nguyen Khang Military Medical Hospital 103, Military Medical Academy
  • Ta Anh Tuan 108 Institute of Clinical Medicine and Pharmaceutical Sciences

Main Article Content

Keywords

Stage 5 chronic kidney disease, maintenance hemodialysis, chronic periodontitis, management and treatment

Abstract

Objective: To survey the results of treatment periodontitis in patients with stage 5 chronic kidney disease on maintenance hemodialysis. Subject and method: Prospective, cross-sectional, longitudinal study after intervention to treat periodontitis in 59 patients with stage 5 chronic kidney disease on maintenance hemodialysis. Result: The proportion of patients with symptoms of bad breath, pain and bleeding gums significantly decreased, p<0.001. The mean values of residue index, tartar index, oral hygiene score, basal periodontal index, gingival index, and degree of tooth mobility after treatment were lower than before treatment, p<0.001. The number of WBC, N and the rate of increase of WBC, N as well as the concentration of CRP as well as the rate of increase of plasma CRP were significantly lower than that before treatment, p<0.001. The rate of patients regrow bacteria after 1 week of treatment was low, only 10.2%. Gum pocket depth > 6.75mm; hemoglobin < 80g/l had a predictive value of still having bacteria after 1 week of treatment, p<0.001. Conclusion: Treatment of periodontitis in patients with stage 5 chronic kidney disease on maintenance hemodialysis gave good results.

Article Details

References

1. Hajishengallis G (2015) Periodontitis: From microbial immune subversion to systemic inflammation. Nat Rev Immunol 15(1): 30-44.
2. Bộ Y tế (2015) Viêm quanh răng tiến triển chậm. Hướng dẫn chẩn đoán và điều trị một số bệnh về răng hàm mặt. Nhà xuất bản Y học, tr. 30-35.
3. Nguyễn Thị Hồng Minh (2010) Nghiên cứu các vi khuẩn gây bệnh viêm quanh răng và ứng dụng điều trị trên lâm sàng. Luận án Tiến sỹ, Trường Đại học Y Hà Nội.
4. Nguyễn Thị Mai Phương (2016) Định lượng Actinobacillus actinomycetemcomitans, porphyromonas gingivalis trong viêm quanh răng bằng realtime PCR và đánh giá hiệu quả của phương pháp điều trị viêm quanh răng không phẫu thuật. Luận án Tiến sỹ. Trường Dại học Y Hà Nội.
5. Kadiroglu AK, Kadiroglu ET, Sit D et al (2006) Periodontitis is an important and occult source of inflammation in hemodialysis patients. Blood. Purif 24: 400-404.
6. Yazdi FK, Karimi N, Rasouli M et al (2013) Effect of nonsurgical periodontal treatment on C-reactive protein levels in maintenance hemodialysis patients. Ren. Fail 35: 711-717.
7. de Souza CM, Braosi AP, Luczyszyn SM et al (2014) Association among oral health parameters, periodontitis, and its treatment and mortality in patients undergoing hemodialysis. J. Periodontol 85: 169-178.
8. Zhou M, Du Y, Wu Y et al (2021) Analysis of inflammatory factor levels in serum and risk factors in patients with chronic renal failure undergoing maintenance hemodialysis. Am J Transl Res 13(6): 6994-7000.