ISSN: 1859 - 2872
The study on the hemodynamic effects of sevoflurane and propofol in cardiac surgery with cardiopulmonary bypass
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Abstract
Objective: To evaluate the hemodynamic effects of anesthesia with inhalation of sevoflurane and total intravenous anaesthesia with propofol in patients undergoing cardiac surgery with cardiopulmonary bypass. Subject and method: Fifty-six patients undergoing cardiac surgery with cardiopulmonary bypass were randomly divided into two groups of 28 each. Group S was anesthetized with sevoflurane while group P received total intravenous anesthesia (TIVA) with propofol. Result: Group P had systolic, diastolic and mean blood pressure just before cardiopulmonary bypass, 15 minutes after cardiopulmonary bypass and the end of surgery; central venous oxygen saturation (ScvO2) after aortic unclamping were lower, the rate of using vasopressors and inotropes during and after surgery, the amount of ephedrine using during surgery were higher than group S with p<0.05. Conclusion: General anesthesia with sevoflurane was more hemodynamically stable than total intravenous anesthesia with propofol in patients undergoing cardiac surgery with cardiopulmonary bypass.
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References
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