Evaluate the results of treatment for unrupture ectopic pregnancy with single dose methotrexate
Main Article Content
Keywords
Abstract
Objective: To evaluate the result and that factors related to the success of treatment for unrupture ectopic pregnancy with single dose methotrexate. Subject and method: A prospective trial study was conducted on 30 patient with single dose methotrexate (MTX) for the treatment of ectopic unrupture pregnancy. Result: The overall rate of success 86.7% in which the first inject was 80%, the second inject was 13.3%, the third inject was 6.67%. With the first injection, level of serum betaHCG < 1000UI/L, rate of success was 100%, 1000 - 3000UI/L was: 86.67%, 3000 - 5000UI/L was 33.33%. The size of ectopic pregnancy mass < 2.5cm the rate of success was 92.3%, > 2.5cm was 50%. Conclusion: The rate of successes on treatment unruptered ectopic pregnancy with single dose MTX was 86.7%. The rate of successes depends on the intital level of serum βhCG and size of ectopic pregnancy mass.
Article Details
References
2. Hà Minh Tuấn (2010) Nghiên cứu điều trị chửa ngoài tử cung chưa vỡ bằng methotrexat tại Bệnh viện Phụ sản Trung ương năm 2009. Luận văn tốt nghiệp bác sĩ chuyên khoa II, Đại học Y Hà Nội.
3. Nguyễn Văn Học (2005) Nghiên cứu sử dụng MTX trong điều trị chửa ngoài tử cung chưa vỡ tại Bệnh viện Phụ sản Hải Phòng. Luận án Tiến sỹ Y học, Học viện Quân y, năm 2005.
4. Vũ Thanh Vân (2006) Đánh giá hiệu quả của MTX trong điều trị chửa ngoài tử cung tại Bệnh viện Phụ sản Trung ương. Luận văn tốt nghiệp bác sĩ nội trú, Trường Đại học Y Hà Nội, năm 2006.
5. Barnhart K, Gabriella G, Rachel A, Mary S (2003) The management of ectopic pregnancy: A meta-analysis comparing single dose anhd multidose regime's. Obst. and Gynecol 101: 778-784.
6. Lipcom Gary H, Karen J, Derita B, (1999) Management of separation pain after single dose methotraxate therapy for ectopic pregnancy. Obst. and Gynecol 93(4): 590-593.
7. Mahvash Z, Taghi R, Morjigan B (2008) Comparison of single and multidose of methotraxate in medical treat of ectopic pregnancy. Par J Med Sci 24(4): 586-589.
8. Ling FW (1993) Methotrexat treatment of un-ruptured ectopic pregnancy: A report of 100 cases. Obstet Gynecol 168: 1759-1765.