ISSN: 1859 - 2872
A value assessment of modified Amsterdam index forecast the risk for osteoporosis in patients with rheumatoid arthritis
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Abstract
Objective: To assess the value of the modified Amsterdam index forecast the risk for osteoporosis in patients with rheumatoid arthritis (RA). Subjects and method: A descriptional and cross-sectional study on 128 inpatients with RA examined in Department of Rheumatology at the Bach Mai Hospital. Result: The high risk for osteoporosis according to the modified Amsterdam index was 84.4%. The modified Amsterdam index provided a sensitivity of 97.44%, a specificity of 21.35%, a positive predictive value of 35.2%, and the area under the curve ROC (ROC AUC) of 0.64 with 95% CI from 0.55 to 0.73 at the femoral neck for identifying osteoporosis in our study population. While changing the threshold for weight indicator from less than 50kg in term of scoring indicator increased the specificity up to 35.96% and ROC AUC to 0.69 with 95%CI from 0.59 to 0.78, the sensitivity reduced to 89.74%. Conclusion: The high risk of osteoporosis interpreted by the modified Amsterdam index in patients with RA was 84.4%. It is feasible to employ the modified Amsterdam index to screen for osteoporosis among patients with RA in order to consequently measure bone mineral density for further intervention.
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