Khảo sát tính đề kháng kháng sinh của một số loài vi khuẩn tại một số khoa lâm sàng trọng điểm ở bệnh viện trường Đại học Y Dược Huế năm 2019

Abstract

Objective: To determine antibiotic resistance of common pathogenical bacteria isolated in key clinical departments at Hue University of Medicine and Pharmacy Hospital in 2019. Subject and method: Use of the agar disk diffusion method to test the susceptibility to antimicrobial agents of 984 bacterial strains from infected patients hospitalized in 4 key clinical departments from 5307 bacteria identification tests which 1129 cultures were positive with 1510 isolated strains at Hue University of Medicine and Pharmacy Hospital in 2019. Result: S. aureus strains that isolated from Department of Trauma, Department of General Internal Medicine, Department of Resuscitation Anesthesia-ICU were highly resistant (> 80%) to cefoxitin, and erythromycin. Meanwhile, in the Department of Urology, S. aureus strains were resistant mainly to quinolone group antibiotics such as norfloxacin (100.0%). The strains of Pseudomonas aeruginosa, E. coli, Klebsiella spp. which isolated in the Department of Urology especially high resistance (> 80%) to many antibiotics. Antibiotics were resistant at different departments in high rate (> 80%) that are in Department of Trauma with cefotaxime; Department of Urology with cefepime, ciprofloxacin; Department of General Internal Medicine with cefoxitin and Department of Resuscitation Anesthesia-ICU with clindamycin… So, the strains of bacteria isolated were not the same, their resistance levels were quite different among key clinical departments. Conclusion: The antibiotic resistance of pathogenic bacteria in key clinical departments is very high and quite different among departments.