ISSN: 1859 - 2872
Case report: Cervical lymph node metastasis in occult papillary thyroid carcinoma
Main Article Content
Keywords
Thyroid, papillary carcinoma, lymph node metastasis, occult carcinoma
Abstract
We reported two cases of cervical lymph node metastasis of papillary thyroid carcinoma (PTC) without detecting primary tumors based on ultrasonography. Even, in one case, no primary tumor was found based on histopathology after total thyroidectomy of that PTC metastasis to lateral cervical lymph nodes was previously detected. Histopathology result of cervical lymph node metastasis of PTC was additionally confirmed through immunohistochemistry with TTF1, thyroglobulin. Both cases underwent total thyroidectomy with central lymph node dissection, radioactive iodine therapy and non-recurrent follow-up for 24 months. Thereby, we reviewed medical literature occult PTC to comprehend further biological characteristics of PTC
Article Details
References
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12. Zheng XQ, Wei SF, Han Y et al (2013) Papillary microcarcinoma of the thyroid: Clinical characteristics and BRAF(V600E) mutational status of 977 cases. Annals of Surgical Oncology 20(7): 2266-2273.
13. Tastekin E, Can N, Ayturk S (2016) Clinically undetectable occult thyroid papillary carcinoma presenting with cervical lymph node metastasis. Acta Endocrinol (Buchar) 12(1): 72-76.
2. Maceri DR, Babyak J, Ossakow SJ (1986) Lateral neck mass. Sole presenting sign of metastatic thyroid cancer. Arch Otolaryngol Head Neck Surg 112(1): 47-49.
3. Ito Y, Hirokawa M, Fukushima M (2008) Occult papillary thyroid carcinoma: Diagnostic and clinical implication in the era of routine ultrasonography. World Journal of Surgey 32: 1955-1960.
4. Mazzaferri EL, Kloos RT (2001) Clinical review 128: current approaches to primary therapy for papillary and follicular thyroid cancer. J Clin Endocrinol Metab 86: 1447-1463.
5. Park CS, Min JS (1989) Lateral neck mass as the initial manifestation of thyroid carcinoma. Head Neck 11(5): 410-413.
6. Ito Y, Amino N, Ota H et al (2007) Ultrasonographic evaluation of thyroid nodules in 900 patients: comparison among ultraso- nographic, cytological, and histological findings. Thyroid 17: 1269-1276.
7. Park JS, Son KR, Na DG et al (2009) Performance of preoperative sonographic staging of papillary thyroid carcinoma based on the sixth edition of the AJCC/UICC TNM classification system. AJR Am J Roentgenol 192(1): 66-72.
8. Li J, Wang Q , Wang L et al (2019) Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer. Oncol Lett 18(3): 2316-2321.
9. Ahn JE, Lee JH, Yi JS et al (2008) Diagnostic accuracy of CT and ultrasonography for evaluating metastatic cervical lymph nodes in patients with thyroid cancer. World J Surg 32(7): 1552-1558.
10. Hegedus L (2001) Thyroid ultrasound. Endocrinol Metab Clin North Am 30: 339.
11. Haugen BR, Alexander EK, Bible KC et al (2016) 2015 american thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: The american thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid 26(1): 1-133.
12. Zheng XQ, Wei SF, Han Y et al (2013) Papillary microcarcinoma of the thyroid: Clinical characteristics and BRAF(V600E) mutational status of 977 cases. Annals of Surgical Oncology 20(7): 2266-2273.
13. Tastekin E, Can N, Ayturk S (2016) Clinically undetectable occult thyroid papillary carcinoma presenting with cervical lymph node metastasis. Acta Endocrinol (Buchar) 12(1): 72-76.
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Published
Apr 1, 2021
Section
Articles
How to Cite
HạnhN. T. M., NhungN. T., & Ánh N. T. N. (2021). Case report: Cervical lymph node metastasis in occult papillary thyroid carcinoma. Tạp Chí Y Dược lâm sàng 108, 16(DB4). https://doi.org/10.52389/ydls.v16iDB4.1019